Personalized genetic prediction

Commentary on the current state of genetic testing for personalized medicine, including promise as well as challenges that still need to be tackled..

Personalized Genetic Prediction: Too Limited, Too Expensive, or Too Soon?
John P.A. Ioannidis
Ann Intern Med 2009;150 139-141
http://www.annals.org/cgi/content/full/150/2/139?etoc

“Genetic epidemiology has identified many common genetic variants that are associated with common diseases, and the list is growing monthly (1, 2). This success has boosted expectations for personalized genetic prediction. According to these expectations, genetic information can tell people about their risk for various diseases and which medications they should use or avoid. However, 2 articles in this issue (3, 4) suggest that this promise may be exaggerated and premature.”