Search challenge 10 examines the issue of how to decide on appropriate screening practices for breast cancer in a young woman whose grandmother developed breast cancer at a relatively young age.
A search that incorporates the main "components" of the question might look something like:
("Breast Neoplasms/diagnosis"[Majr] OR breast neoplasms/genetics[majr]) AND (inherited[tiab] OR familial[tiab] OR high risk[tiab] OR family history[tiab] OR grandmother[tiab] OR pedigree[tiab] OR second degree[tiab] OR heredity[tiab] OR hereditary[tiab]) AND (age factors[mh] OR risk[mh] OR predictive value of tests[mh] OR sensitivity and specificity[mh]) AND (diagnostic imaging[majr] OR mass screening[majr]) AND english[la] AND humans[mh] NOT (case reports[pt] OR letter[pt] OR comment[pt] OR editorial[pt])
A few good articles on the topics, drawn from PubMed and a Google search: Claus EB, Risch N, Thompson WD. Autosomal dominant inheritance of early-onset breast cancer. Implications for risk prediction. Cancer. 1994 Feb 1;73(3):643-51. PMID: 8299086
Kriege M, Brekelmans CT, Obdeijn IM, Boetes C, Zonderland HM, Muller SH, Kok T, Manoliu RA, Besnard AP, Tilanus-Linthorst MM, Seynaeve C, Bartels CC, Kaas R, Meijer S, Oosterwijk JC, Hoogerbrugge N, Tollenaar RA, Rutgers EJ, de Koning HJ, Klijn JG. Factors affecting sensitivity and specificity of screening mammography and MRI in women with an inherited risk for breast cancer. Breast Cancer Res Treat. 2006 Nov;100(1):109-19. Epub 2006 Jun 22. PMID: 16791481
Kriege M, Brekelmans CT, Boetes C, Besnard PE, Zonderland HM, Obdeijn IM, Manoliu RA, Kok T, Peterse H, Tilanus-Linthorst MM, Muller SH, Meijer S, Oosterwijk JC, Beex LV, Tollenaar RA, de Koning HJ, Rutgers EJ, Klijn JG; Magnetic Resonance Imaging Screening Study Group. Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition. N Engl J Med. 2004 Jul 29;351(5):427-37. PMID: 15282350
NCCN practice guidelines in oncology: Breast cancer risk reduction, 2008. Vol. 1, http://www.nccn.org/professionals/physician_gls/PDF/breast_risk.pdf
NCCN practice guidelines in oncology: Breast cancer screening and diagnosis, 2008. Vol. 1, http://www.nccn.org/professionals/physician_gls/PDF/breast-screening.pdf
NCCN practice guidelines in oncology: Genetic/familial high risk assessment: Breast and ovarian, 2008. Vol. 1, http://www.nccn.org/professionals/physician_gls/PDF/genetics_screening.pdf
Saslow D, Boetes C, Burke W, Harms S, Leach MO, Lehman CD, Morris E, Pisano E, Schnall M, Sener S, Smith RA, Warner E, Yaffe M, Andrews KS, Russell CA; American Cancer Society Breast Cancer Advisory Group. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin. 2007 Mar-Apr;57(2):75-89. Erratum in: CA Cancer J Clin. 2007 May-Jun;57(3):185. PMID: 17392385
Smith RA, Saslow D, Sawyer KA, Burke W, Costanza ME, Evans WP 3rd, Foster RS Jr, Hendrick E, Eyre HJ, Sener S; American Cancer Society High-Risk Work Group;American Cancer Society Screening Older Women Work Group; American Cancer Society Mammography Work Group; American Cancer Society Physical Examination Work Group; American Cancer Society New Technologies Work Group; American Cancer Society Breast Cancer Advisory Group. American Cancer Society guidelines for breast cancer screening: update 2003.CA Cancer J Clin. 2003 May-Jun;53(3):141-69.PMID: 12809408
Yu J, Park A, Morris E, Liberman L, Borgen PI, King TA. MRI screening in a clinic population with a family history of breast cancer. Ann Surg Oncol. 2008 Feb;15(2):452-61. Epub 2007 Nov 17. PMID: 18026801
Labels: search challenge