The October 2007 JMLA case talks a lot about how drugs, in this case vancomycin, work within the body, and how clinicians and researchers explore and understand these mechanisms -- pharmacokinetics and pharmacodynamics are two key concepts introduced in the case and worth further exploration.Pharmacokinetics:
This PowerPoint presentation from the University of Connecticut, A Short Course in Pharmacokinetics
, gives a great overview of what pharmacokinetics is, what it means for drug delivery and metabolism in humans, and an explanation of a lot of related terminology.This one from Kennesaw
is also a good basic introduction.Pharmacodynamics: This overview from Howard University
provides a great discussion of pharmacodynamics and how this concept is used to explain and understand how drugs actually affect the human body and its systems.